BDBM50593515 CHEMBL5180338

SMILES COc1cc(ccc1O)[C@H]1Oc2cc3c(NC(=O)[C@@]3(O)CC#N)cc2[C@@H]1CO

InChI Key InChIKey=GZFXNLYYNNGWHS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50593515   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50593515(CHEMBL5180338)
Affinity DataEC50:  970nMAssay Description:Activation of human SHP2 (205 to 597 residues) expressed in Escherichia coli BL21 using 8-difluoro-4-methylumbelliferyl phosphate as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed