BDBM50593352 CHEMBL5208471

SMILES O=C(COc1ccc(\C=C2\SC(=O)NC2=O)cc1)N1N=C(CC1c1ccccc1)c1ccccc1

InChI Key InChIKey=VLCQEDLNVOGCBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50593352   

TargetHistone deacetylase 4(Human)
Bharati Vidyapeeth'S College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50593352(CHEMBL5208471)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-SUMO-tagged C-terminal SII-tagged HDAC4 expressed in Escherichia coli (BL21) DE3 pLysS cells using Bo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Bharati Vidyapeeth'S College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50593352(CHEMBL5208471)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His6-SUMO-tagged C-terminal SII-tagged HDAC8 expressed in Escherichia coli (BL21) DE3 pLysS cells using Bo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed