BDBM50593299 CHEMBL5179252

SMILES NS(=O)(=O)c1cccc(Nc2nccc(Nc3ccc4oc(=O)[nH]c4c3)n2)c1

InChI Key InChIKey=PVPNFEKZUBZJJP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50593299   

TargetJAK3/JAK1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50593299(CHEMBL5179252)
Affinity DataIC50: 237nMAssay Description:Inhibition of JAK1/JAK3 in human primary T-cells assessed as reduction of IL-2 stimulated STAT5 phosphorylation preincubated for 1 hr followed by IL-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed