BDBM50593294 CHEMBL5189275

SMILES Cc1cnc(Nc2cccc(c2)S(N)(=O)=O)nc1Nc1ccc2oc(=O)n(C)c2c1

InChI Key InChIKey=ASQCLYSQNKEOCC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50593294   

TargetJAK3/JAK1(Human)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50593294(CHEMBL5189275)
Affinity DataIC50: 65nMAssay Description:Inhibition of JAK1/JAK3 in human primary T-cells assessed as reduction of IL-2 stimulated STAT5 phosphorylation preincubated for 1 hr followed by IL-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed