BDBM50593285 CHEMBL5188760

SMILES Cn1cnnc1CC1(COC1)c1cc(nc(c1)N1Cc2c(cc(CNC3(C)CCC3)cc2C(F)(F)F)C1=O)C1CC1

InChI Key InChIKey=MNELVOQWIAZVEZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50593285   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50593285(CHEMBL5188760)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as reduction in LCK ubiquitination preincubated for 60 mins followed by kinase mix addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed