BDBM50593283 CHEMBL5177497

SMILES C[C@@H](NC1(C)CCC1)c1cc2C(=O)N(Cc2c(c1)C(F)(F)F)c1cccc(c1)C1(COC1)[C@@H](F)c1nncn1C

InChI Key InChIKey=NJOKETZTARBFPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50593283   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50593283(CHEMBL5177497)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as reduction in LCK ubiquitination preincubated for 60 mins followed by kinase mix addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed