BDBM50593277 CHEMBL5183661

SMILES CCOC(=O)c1[nH]c2nc1-c1ccc(NC(=O)OC)cc1NC(=O)C(C)(C)CCC[C@@H]2c1ccc(c[n+]1[O-])-c1cccc(Cl)c1F

InChI Key InChIKey=LGAFIEKLHAVOLZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50593277   

TargetCoagulation factor XI(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50593277(CHEMBL5183661)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human coagulation factor XIa using GPR-AFC as substrate preincubated for 30 mins followed by substrate addition and measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed