BDBM50593112 CHEMBL5200361

SMILES CCNNC(=O)c1ccc(Cn2c3ccccc3c3cnccc23)cc1

InChI Key InChIKey=VTQDXRVQFUAWGO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50593112   

TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50593112(CHEMBL5200361)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50593112(CHEMBL5200361)
Affinity DataIC50: 3.23E+3nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50593112(CHEMBL5200361)
Affinity DataIC50: 4.61E+3nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50593112(CHEMBL5200361)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed