BDBM50593057 CHEMBL5191038

SMILES CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O

InChI Key InChIKey=NOBVBYDJFSMLOT-UHFFFAOYSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50593057   

TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Missouri-Kansas City

Curated by ChEMBL
LigandPNGBDBM50593057(CHEMBL5191038)
Affinity DataIC50: 6.07E+3nMAssay Description:Inhibition of human recombinant PD-1/PD-L1 interaction preincubated with compound for 2 hrs followed by PD-1 protein addition and measured after 1.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProgrammed cell death protein 1(Mouse)
University of Missouri-Kansas City

Curated by ChEMBL
LigandPNGBDBM50593057(CHEMBL5191038)
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibition of mouse recombinant PD-1/PD-L1 interaction preincubated with compound for 2 hrs followed by PD-1 protein addition and measured after 1.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Missouri-Kansas City

Curated by ChEMBL
LigandPNGBDBM50593057(CHEMBL5191038)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of human PD-1/PD-L1 interaction by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Nantes University

Curated by ChEMBL
LigandPNGBDBM50593057(CHEMBL5191038)
Affinity DataKd:  366nMAssay Description:Binding affinity to CM5 sensor chip immobilized human recombinant extracellular domain PD-L1 assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Nantes University

Curated by ChEMBL
LigandPNGBDBM50593057(CHEMBL5191038)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of human recombinant extracellular domain PD-L1 in human DU-145 cells incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed