BDBM50593055 CHEMBL5184371

SMILES [H][C@]1(NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(N)=O)NC(C)=O)[C@@H](C)O

InChI Key InChIKey=KGPIBWMECOGVNE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50593055   

TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Missouri-Kansas City

Curated by ChEMBL
LigandPNGBDBM50593055(CHEMBL5184371)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant PD-1/PD-L1 interaction preincubated with compound for 2 hrs followed by PD-1 protein addition and measured after 1.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProgrammed cell death protein 1(Mouse)
University of Missouri-Kansas City

Curated by ChEMBL
LigandPNGBDBM50593055(CHEMBL5184371)
Affinity DataIC50: 552nMAssay Description:Inhibition of mouse recombinant PD-1/PD-L1 interaction preincubated with compound for 2 hrs followed by PD-1 protein addition and measured after 1.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
University of Missouri-Kansas City

Curated by ChEMBL
LigandPNGBDBM50593055(CHEMBL5184371)
Affinity DataIC50: 119nMAssay Description:Inhibition of human PD-1/PD-L1 interaction by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed