BDBM50593026 CHEMBL5198837

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1c(F)cccc1F)B(O)O

InChI Key InChIKey=QTRFWSIBLJYXFJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50593026   

TargetProteasome subunit beta type-5(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50593026(CHEMBL5198837)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProteasome subunit beta type-5(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50593026(CHEMBL5198837)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of 20S proteasome beta5 subunit (unknown origin) using Suc-LLVY-AMC as flurogenic substrate measured after 1 hr by fluorescence based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProteasome subunit beta type-2(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50593026(CHEMBL5198837)
Affinity DataIC50: 101nMAssay Description:Inhibition of 20S proteasome beta2 subunit (unknown origin) using Boc-LRR-AMC as flurogenic substrate measured after 1 hr by fluorescence based analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProteasome subunit beta type-1(Human)
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50593026(CHEMBL5198837)
Affinity DataIC50: 114nMAssay Description:Inhibition of 20S proteasome beta1 subunit (unknown origin) using Z-LLE-AMC as flurogenic substrate measured after 1 hr by fluorescence based analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed