BDBM50592916 CHEMBL5206486

SMILES C[C@@H](N1C(=O)CCC1=O)C(=O)NCc1ccccc1

InChI Key InChIKey=XVSYJYYNUSOPAQ-UHFFFAOYSA-N

Data  2 KI  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50592916   

TargetExcitatory amino acid transporter 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50592916(CHEMBL5206486)
Affinity DataEC50:  11nMAssay Description:Activation of human EAAT2 transfected in COS7 cells assessed as glutamate uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetExcitatory amino acid transporter 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50592916(CHEMBL5206486)
Affinity DataEC50:  25nMAssay Description:Activation of human EAAT2 transfected in Glial cells assessed as glutamate uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAlbumin(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50592916(CHEMBL5206486)
Affinity DataKd:  1.97E+6nMAssay Description:Binding affinity to human serum albumin assessed as dissociation constant by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSynaptic vesicle glycoprotein 2A(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50592916(CHEMBL5206486)
Affinity DataKi: >2.50E+5nMAssay Description:Binding affinity to human SV2A in presence of levetiracetam by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSynaptic vesicle glycoprotein 2A(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50592916(CHEMBL5206486)
Affinity DataKi: >2.50E+5nMAssay Description:Binding affinity to mouse SV2A in presence of levetiracetam by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed