BDBM50592852 CHEMBL5204662

SMILES OC(=O)CCNC(=O)c1ccc(cc1)-c1cn(nn1)-c1ccc(O)c(c1)C(O)=O

InChI Key InChIKey=IEQRLIKEMUPGKV-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50592852   

TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50592852(CHEMBL5204662)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of recombinant human Sirt5 incubated for 1 hr by FLUOR DE LYS fluorometric microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50592852(CHEMBL5204662)
Affinity DataEC50:  1.20E+3nMAssay Description:Binding affinity to Sirt5 in human MCF7 cell lysate by pull down assay based LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNucleoside diphosphate kinase, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50592852(CHEMBL5204662)
Affinity DataEC50:  7.80E+3nMAssay Description:Binding affinity to NME4 in human MCF7 cell lysate by pull down assay based LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutaryl-CoA dehydrogenase, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50592852(CHEMBL5204662)
Affinity DataEC50:  5.95E+4nMAssay Description:Binding affinity to GCDH in human MCF7 cell lysate by pull down assay based LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Ludwig-Maximilians University

Curated by ChEMBL
LigandPNGBDBM50592852(CHEMBL5204662)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human SIRT5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed