BDBM50592581 CHEMBL5180874

SMILES C[C@]1(CN2Cc3nc(sc3C2)-c2ccc(F)cc2)CN=C(N)O1

InChI Key InChIKey=WUQLEOOOWJRETO-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50592581   

TargetCytochrome P450 1A2(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50592581(CHEMBL5180874)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 2B6(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50592581(CHEMBL5180874)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 2C8(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50592581(CHEMBL5180874)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50592581(CHEMBL5180874)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50592581(CHEMBL5180874)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50592581(CHEMBL5180874)
Affinity DataIC50: 8.06E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50592581(CHEMBL5180874)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592581(CHEMBL5180874)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592581(CHEMBL5180874)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of human Cav1.2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetKinesin-like protein KIF21A(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50592581(CHEMBL5180874)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of Kir2.1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
LigandPNGBDBM50592581(CHEMBL5180874)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of Kv4.3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Wuxi Apptec

Curated by ChEMBL
LigandPNGBDBM50592581(CHEMBL5180874)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of NaV 1.5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed