BDBM50592452 CHEMBL5191468

SMILES Oc1cccc(c1)-c1nn(cc1-c1ccnc(NCCCNC(=O)Nc2ccc(F)cc2)c1)-c1ccccc1

InChI Key InChIKey=BCNMJLRKWYKBBZ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50592452   

TargetMitogen-activated protein kinase 10(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592452(CHEMBL5191468)
Affinity DataIC50: 97nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592452(CHEMBL5191468)
Affinity DataIC50: 98nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592452(CHEMBL5191468)
Affinity DataIC50: 791nMAssay Description:Inhibition of FLT4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592452(CHEMBL5191468)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of JNK1-alpha-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592452(CHEMBL5191468)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of JNK2-alpha-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592452(CHEMBL5191468)
Affinity DataIC50: 3.84E+3nMAssay Description:Inhibition of JNK3 in human HEK293 cells transfected with JNK3-NanoLuc fusion vector measured after 1 hr by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592452(CHEMBL5191468)
Affinity DataIC50: 5.54E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) using EOMCC as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592452(CHEMBL5191468)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using BOMCC as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592452(CHEMBL5191468)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of hERG measured by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed