BDBM50592449 CHEMBL5201911

SMILES Oc1cccc(c1)-c1nn(cc1-c1ccnc(NCCNC(=O)Nc2cccc(c2)C(F)(F)F)c1)-c1ccccc1

InChI Key InChIKey=HGCVWICUBZDORS-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50592449   

TargetMitogen-activated protein kinase 10(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592449(CHEMBL5201911)
Affinity DataIC50: 99nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592449(CHEMBL5201911)
Affinity DataIC50: 100nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592449(CHEMBL5201911)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDGFRalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592449(CHEMBL5201911)
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of JNK3 in human HEK293 cells transfected with JNK3-NanoLuc fusion vector measured after 1 hr by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592449(CHEMBL5201911)
Affinity DataIC50: 6.24E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) using EOMCC as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592449(CHEMBL5201911)
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using BOMCC as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50592449(CHEMBL5201911)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of hERG measured by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed