BDBM50592259 CHEMBL5208297

SMILES NC(=O)\C=C\c1ccc(COc2ccc(cc2)-n2cc3cccc(C(N)=O)c3n2)cc1

InChI Key InChIKey=IPPGXRJXMXVNLN-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50592259   

TargetPoly [ADP-ribose] polymerase 1(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50592259(CHEMBL5208297)
Affinity DataIC50: 227nMAssay Description:Inhibition of PARP-1 derived from human HeLa cell nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50592259(CHEMBL5208297)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of HDAC derived from human HeLa cell nucleusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50592259(CHEMBL5208297)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50592259(CHEMBL5208297)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50592259(CHEMBL5208297)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50592259(CHEMBL5208297)
Affinity DataIC50: 510nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50592259(CHEMBL5208297)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Qingdao University Medical College

Curated by ChEMBL
LigandPNGBDBM50592259(CHEMBL5208297)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed