BDBM50592198 CHEMBL5200076

SMILES Cc1c(F)ccc2[nH]c(nc12)-c1cncc(-c2cc(F)cc(c2)C#N)c1N1CC[C@H](N)C1

InChI Key InChIKey=NWJHUIUKWIDBNZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50592198   

TargetSomatostatin receptor type 5(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592198(CHEMBL5200076)
Affinity DataEC50:  0.650nMAssay Description:Agonist activity at human SST5 expressed in CHO-K1 cells assessed as reduction in NKH477-induced intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSomatostatin receptor type 5(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592198(CHEMBL5200076)
Affinity DataEC50:  0.631nMAssay Description:Agonist activity at human SST5 expressed in CHO-K1 cells assessed as reduction in NKH477-induced intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed