BDBM50592186 CHEMBL5177695

SMILES Cc1cc(F)cc(c1)-c1cncc(-c2nc3c(F)cc(F)cc3[nH]2)c1N1CC[C@H](N)C1

InChI Key InChIKey=PEKSFTWITUWNKO-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50592186   

TargetSomatostatin receptor type 5(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592186(CHEMBL5177695)
Affinity DataEC50:  5.40nMAssay Description:Agonist activity at human SST5 expressed in CHO-K1 cells assessed as reduction in NKH477-induced intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSomatostatin receptor type 5(Human)
Crinetics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50592186(CHEMBL5177695)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human SST5 expressed in CHO-K1 cells assessed as reduction in NKH477-induced intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed