BDBM50592063 CHEMBL5178437

SMILES CN1CCN(CC1)c1ccc(Nc2nc(N)c(s2)C(=O)c2c(C)cc(C)cc2C)cc1

InChI Key InChIKey=HZPVUKVIGLCUPG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50592063   

TargetCyclin-dependent kinase 11A(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50592063(CHEMBL5178437)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of N-terminus or C-terminus NLuc fused CDK11A (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50592063(CHEMBL5178437)
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant full length GST-tagged CDK4/Cyclin D1 expressed in Baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50592063(CHEMBL5178437)
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant full length GST-tagged CDK6/Cyclin D1 expressed in Baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50592063(CHEMBL5178437)
Affinity DataIC50: 71nMAssay Description:Inhibition of human recombinant full length His-tagged CDK9/Cyclin T1 expressed in Baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed