BDBM50591762 CHEMBL470172

SMILES [H][C@@]1(O[C@H]2[C@H](O)[C@H](O[C@@]([H])(O[C@H]3CC[C@@]4(C)[C@@]([H])(CC[C@]5(C)[C@]4([H])CC=C4[C@]6([H])CC(C)(C)CC[C@@]6(CC[C@@]54C)C(O)=O)C3(C)C)[C@@H]2O)C(O)=O)OC[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=HWYBGIDROCYPOE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50591762   

TargetSentrin-specific protease 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50591762(CHEMBL470172)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of SENP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSentrin-specific protease 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50591762(CHEMBL470172)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of SENP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetSentrin-specific protease 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50591762(CHEMBL470172)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of recombinant human SENP1 catalytic domain using RanGAP1 as substrate preincubated for 10 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSentrin-specific protease 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50591762(CHEMBL470172)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of human SENP1 catalytic domain assessed as reduction in deSUMOylation of RanGAP1-SUMO2 using RanGAP1-SUMO2 as substrate by fluorescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed