BDBM50591652 CHEMBL5202431

SMILES CCN1CCN(CC1)c1cc(Nc2ncc(s2)C(=O)Nc2ccc(F)cc2N)ncn1

InChI Key InChIKey=FOYDGOBFRZQHEU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50591652   

TargetHistone deacetylase 1(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50591652(CHEMBL5202431)
Affinity DataIC50: 810nMAssay Description:Inhibition of full-length recombinant human HDAC1 expressed in baculovirus infected Hi-5 insect cells using AcLys-Tyr-Lys(e-acetyl)-AMC as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50591652(CHEMBL5202431)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of BCR-ABL (unknown origin) incubated for 1 hr in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50591652(CHEMBL5202431)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50591652(CHEMBL5202431)
Affinity DataIC50: 810nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed