BDBM50591647 CHEMBL5191354

SMILES [H][C@]12COC(=O)[C@]1([H])[C@H](c1cc(OC)c(OC(=O)CC(=O)Nc3ccc(cc3)C(=O)Nc3ccccc3N)c(OC)c1)c1cc3OCOc3cc1C2

InChI Key InChIKey=RUZISCYMEUSGBU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50591647   

TargetHistone deacetylase 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591647BDBM50591647(CHEMBL5191354)
Affinity DataIC50: 750nMAssay Description:Inhibition of recombinant human HDAC2 expressed in baculovirus infected Hi-5 insect cells using Ac-Lys-Tyr-Lys (epsilon-acetyl)-AMC as substrate incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591647BDBM50591647(CHEMBL5191354)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of human recombinant HDAC2 extracted from baculovirus infected Insect cells using Ac-Lys-Tyr-Lys (acetyl)-AMC as substrate incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591647BDBM50591647(CHEMBL5191354)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of recombinant human HDAC3 expressed in baculovirus infected Hi-5 insect cells using Ac-Lys-Tyr-Lys (epsilon-acetyl)-AMC as substrate incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50591647BDBM50591647(CHEMBL5191354)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human HDAC1 expressed in baculovirus infected Hi-5 insect cells using Ac-Lys-Tyr-Lys (epsilon-acetyl)-AMC as substrate incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed