BDBM50591380 CHEMBL5180611::US20240190828, Compound 34

SMILES Cc1cccc(c1)C1NC(=O)c2c(Br)cccc2N1

InChI Key InChIKey=PXWIXTCIXZCREB-UHFFFAOYSA-N

Data  2 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50591380   

TargetProtein polybromo-1(Human)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50591380(CHEMBL5180611 | US20240190828, Compound 34)
Affinity DataIC50: 160nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProtein polybromo-1(Human)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50591380(CHEMBL5180611 | US20240190828, Compound 34)
Affinity DataKd:  4.40E+3nMAssay Description:Binding affinity to His-TEV-tagged recombinant human PBRM1 BD2 transfected in Escherichia coli BL21 (DE3) assessed as dissociation constant at 30 uM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProtein polybromo-1(Human)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50591380(CHEMBL5180611 | US20240190828, Compound 34)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to His-TEV-tagged human PBRM1 BD5 transfected in Escherichia coli BL21 (DE3) assessed as dissociation constant at 30 uM by ITC analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591380(CHEMBL5180611 | US20240190828, Compound 34)
Affinity DataIC50: 160nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetProtein polybromo-1 [200-270](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591380(CHEMBL5180611 | US20240190828, Compound 34)
Affinity DataKd:  4.39E+3nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetProtein polybromo-1 [676-746](Human)
The Medical College of Wisconsin, Inc.

US Patent
LigandPNGBDBM50591380(CHEMBL5180611 | US20240190828, Compound 34)
Affinity DataKd:  2.47E+4nMAssay Description:No detail is given.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent