BDBM50591320 CHEMBL5190700

SMILES C[C@H]1C[C@H](CCO1)N1C(=O)C[C@](C)(NC1=N)c1cccc(NC(=O)c2cccc(c2)C#N)c1Cl

InChI Key InChIKey=AWSRDDSRQUJMAJ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50591320   

TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Ucb

Curated by ChEMBL
LigandPNGBDBM50591320(CHEMBL5190700)
Affinity DataIC50: 7nMAssay Description:Inhibition of Plasmodium falciparum recombinant C-terminal TEV cleavable 8his-tagged PMX by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPlasmepsin IX(Plasmodium falciparum (isolate 3D7))
Ucb

Curated by ChEMBL
LigandPNGBDBM50591320(CHEMBL5190700)
Affinity DataIC50: 142nMAssay Description:Inhibition of Plasmodium falciparum PMIX by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCathepsin D(Human)
Ucb

Curated by ChEMBL
LigandPNGBDBM50591320(CHEMBL5190700)
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetRenin(Human)
Ucb

Curated by ChEMBL
LigandPNGBDBM50591320(CHEMBL5190700)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Ucb

Curated by ChEMBL
LigandPNGBDBM50591320(CHEMBL5190700)
Affinity DataIC50: 7nMAssay Description:Inhibition of PMX in Plasmodium falciparum 3D7 HA epitopeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPlasmepsin IX(Plasmodium falciparum (isolate 3D7))
Ucb

Curated by ChEMBL
LigandPNGBDBM50591320(CHEMBL5190700)
Affinity DataIC50: 142nMAssay Description:Inhibition of PMIX in Plasmodium falciparum 3D7 HA epitopeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPlasmepsin X(Plasmodium falciparum (isolate 3D7))
Ucb

Curated by ChEMBL
LigandPNGBDBM50591320(CHEMBL5190700)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of Plasmodium falciparum Plasmepsin X using Dabcyl-GSMLEVENDAEG-EDANS as substrate preincubated for 30 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed