BDBM50591287 CHEMBL5186881

SMILES CN(C(=O)[C@@H]1C[C@H](O)CN1c1nc(C)cc(C)c1C#N)c1cccc(C)c1

InChI Key InChIKey=PBZCNJWUKKGARR-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50591287   

TargetDNA polymerase theta(Human)
Artios Pharma

Curated by ChEMBL
LigandPNGBDBM50591287(CHEMBL5186881)
Affinity DataKd:  19nMAssay Description:Displacement of tracer from recombinant Tb-labeled DNA polymerase theta (unknown origin) using DNA as substrate preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Artios Pharma

Curated by ChEMBL
LigandPNGBDBM50591287(CHEMBL5186881)
Affinity DataKd:  51nMAssay Description:Displacement of tracer from recombinant Tb-labeled DNA polymerase theta (unknown origin) assessed as end point Kd using DNA as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed