BDBM50591249 CHEMBL5170837

SMILES CN(C(=O)[C@@H]1C[C@@H](O)CN1c1nc(C)cc(c1C#N)C(F)(F)F)c1cccc(C)c1

InChI Key InChIKey=FAQDVYGMYVIYHD-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50591249   

TargetDNA polymerase theta(Human)
Artios Pharma

Curated by ChEMBL
LigandPNGBDBM50591249(CHEMBL5170837)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human full length DNA polymerase theta using DNA substrate measured after 1 hrs in presence of dNTPs by plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDNA polymerase theta(Human)
Artios Pharma

Curated by ChEMBL
LigandPNGBDBM50591249(CHEMBL5170837)
Affinity DataKd:  69nMAssay Description:Displacement of tracer from recombinant Tb-labeled DNA polymerase theta (unknown origin) assessed as end point Kd using DNA as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed