BDBM50590998 CHEMBL5188740

SMILES CC1Cc2nn(CC(=O)N(C)c3ccccc3)c(c2C1)C(F)(F)F

InChI Key InChIKey=UUCDNKWOGSPQGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50590998   

TargetDNA polymerase theta(Human)
Repare Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590998(CHEMBL5188740)
Affinity DataIC50: 950nMAssay Description:Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed