BDBM50590518 CHEMBL5201333

SMILES Cn1ncc(c1-c1sc2ccncc2c1C#N)-c1ccc2c(c1)c(CN)n[nH]c2=O

InChI Key InChIKey=ZKLLHZWAVCQOPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50590518   

TargetProtein arginine N-methyltransferase 5(Human)
Mirati Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590518(CHEMBL5201333)
Affinity DataIC50: 768nMAssay Description:Inhibition of PRMT5 (unknown origin) using H2A and 3H-SAM as substrates preincubated for 20 mins followed by substrate addition incubated for 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed