BDBM50590429 CHEMBL5208447

SMILES CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2ccc(cc2)C(=O)NCCOCCOCCOCCOc2cc(ccc2CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](C(C)C)N2Cc3ccccc3C2=O)-c2scnc2C)c1F

InChI Key InChIKey=OKJXOZINZBWONV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50590429   

TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50590429(CHEMBL5208447)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) using MEK1 (K97R) as substrate in presence of [gamma-33P]ATP by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed