BDBM50590392 CHEMBL5170410

SMILES CCN(CCCCOc1ccc(\C=C\C(=O)N2CCc3ccccc3C2)cc1OC)Cc1ccccc1

InChI Key InChIKey=CGZGXSZYVAXOGJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50590392   

TargetCholinesterase(Horse)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50590392(CHEMBL5170410)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of equine serum BChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50590392(CHEMBL5170410)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine as substrate incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50590392(CHEMBL5170410)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of recombinant human MAO-A assessed as amount of 4-hydroxyquinoline using kynuramine as a substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50590392(CHEMBL5170410)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of recombinant human MAO-B assessed as amount of 4-hydroxyquinoline using kynuramine as a substrate incubated for 30 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50590392(CHEMBL5170410)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of Electrophorus electricus AchE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50590392(CHEMBL5170410)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of BuChE (unknown origin) incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed