BDBM50590375 CHEMBL5187396

SMILES CN(C)C1CCC(CC1)C1(C)Oc2c(O1)c(C)c(cc2Br)C(=O)NCc1c(C)cc(C)[nH]c1=O

InChI Key InChIKey=CHJLMVBYELJCLC-UHFFFAOYSA-N

Data  39 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 39 hits for monomerid = 50590375   

TargetProtein arginine N-methyltransferase 1(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase PRDM9(Homo sapiens)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SETD1B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetN-lysine methyltransferase KMT5A(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SETD2(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetN-lysine methyltransferase SMYD2(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SUV39H1(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SUV39H2(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase KMT5B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 3(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 8(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
Affinity DataIC50: 21nMAssay Description:Inhibition of EZH1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of EZH2 in human HCT-116 cells assessed as inhibition of H3K27me3 incubated for 3 days by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
Affinity DataIC50: 5.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
Affinity DataIC50: 5.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
Affinity DataIC50: 24nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase 2A(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase 2D(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase 2C(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase 2B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-36 specific(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD2(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50590375(CHEMBL5187396)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed