BDBM50590374 CHEMBL5196503

SMILES CCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc(NC(=O)C=C)c1C)-c1ccc(nc1)N1CCNCC1

InChI Key InChIKey=LMOMYFZWGUZCHB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50590374   

TargetHistone-lysine N-methyltransferase EZH2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590374(CHEMBL5196503)
Affinity DataIC50: 47nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590374(CHEMBL5196503)
Affinity DataIC50: 47nMAssay Description:Inhibition of wild-type EZH2 (494 to 737 residues) (unknown origin) expressed in Escherichia coli by AlphaLisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590374(CHEMBL5196503)
Affinity DataIC50: 47nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed