BDBM50590353 CHEMBL5199020

SMILES CCOc1ccc(cc1Cl)C(=O)Cn1c2ccccc2c(=O)n(CC(=O)Nc2ccccc2OC)c1=O

InChI Key InChIKey=BVJNVFFXFHFQRV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50590353   

TargetSphingosine 1-phosphate receptor 2(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50590353(CHEMBL5199020)
Affinity DataIC50: 50nMAssay Description:Displacement of [32P]S1P from human recombinant S1PR2 incubated for 60 mins by competitive binding assay based scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50590353(CHEMBL5199020)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [32P]S1P from human recombinant S1PR1 incubated for 60 mins by competitive binding assay based scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50590353(CHEMBL5199020)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [32P]S1P from human recombinant S1PR3 incubated for 60 mins by competitive binding assay based scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50590353(CHEMBL5199020)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [32P]S1P from human recombinant S1PR4 incubated for 60 mins by competitive binding assay based scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50590353(CHEMBL5199020)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [32P]S1P from human recombinant S1PR5 incubated for 60 mins by competitive binding assay based scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed