BDBM50590269 CHEMBL5187963

SMILES Cc1cccc2c1nc(CSc1ncccn1)[nH]c2=O

InChI Key InChIKey=ANAUZAZPUGQDNM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50590269   

TargetPoly [ADP-ribose] polymerase 2(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590269(CHEMBL5187963)
Affinity DataIC50: 800nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP2 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590269(CHEMBL5187963)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP11 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50590269(CHEMBL5187963)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PARP14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50590269(CHEMBL5187963)
Affinity DataIC50: 800nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590269(CHEMBL5187963)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed