BDBM50590251 CHEMBL5186879

SMILES CN(C)c1ccc(\C=C\[N+]([O-])=O)cc1Nc1ccccn1

InChI Key InChIKey=XHYLNXKQZCIXND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590251   

TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50590251(CHEMBL5186879)
Affinity DataIC50: 3.60E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50590251(CHEMBL5186879)
Affinity DataIC50: 3.70E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed