BDBM50590202 CHEMBL5192115

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)C\C=C(/F)[C@@H](N)Cc1ccc(O)cc1)C(N)=O

InChI Key InChIKey=JRQWLWZTKLOPSQ-UHFFFAOYSA-N

Data  4 KI  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50590202   

TargetDelta-type opioid receptor(Mouse)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50590202(CHEMBL5192115)
Affinity DataIC50: 47nMAssay Description:Agonist activity at FLAG-tagged mouse delta opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin stimulated cAMP produ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Mouse)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50590202(CHEMBL5192115)
Affinity DataIC50: 47nMAssay Description:Agonist activity at FLAG-tagged mouse delta opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin stimulated cAMP produ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50590202(CHEMBL5192115)
Affinity DataEC50:  955nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells co-expressing beta-arrestin2 assessed as beta-arrestin2 recruitment measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50590202(CHEMBL5192115)
Affinity DataEC50:  959nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells co-expressing beta-arrestin2 assessed as beta-arrestin2 recruitment measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50590202(CHEMBL5192115)
Affinity DataIC50: 186nMAssay Description:Agonist activity at FLAG-tagged mouse mu opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin stimulated cAMP producti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50590202(CHEMBL5192115)
Affinity DataIC50: 186nMAssay Description:Agonist activity at FLAG-tagged mouse mu opioid receptor expressed in human HEK293 cells assessed as inhibition of forskolin stimulated cAMP producti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50590202(CHEMBL5192115)
Affinity DataEC50:  2.63E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells co-expressing beta-arrestin2 assessed as beta-arrestin2 recruitment measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50590202(CHEMBL5192115)
Affinity DataEC50:  2.64E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells co-expressing beta-arrestin2 assessed as beta-arrestin2 recruitment measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50590202(CHEMBL5192115)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membrane incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50590202(CHEMBL5192115)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membrane incubated for 90 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50590202(CHEMBL5192115)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHO cell membrane measured after 90 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50590202(CHEMBL5192115)
Affinity DataKi:  94nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHO cell membrane measured after 90 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed