BDBM50590161 CHEMBL5193408

SMILES Cc1oncc1NS(=O)(=O)c1ccc(F)c2ncc(I)cc12

InChI Key InChIKey=VRNAMGPYWFJMKJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590161   

TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50590161(CHEMBL5193408)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in 5-methylcytosine oxidation preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET2(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50590161(CHEMBL5193408)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of N-terminal His6-tagged TET2 (unknown origin) expressed in Escherichia coli assessed as reduction in hmC and fC levels preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed