BDBM50590139 CHEMBL5196919

SMILES CC(C)(C)c1ccc(cc1)-c1nnc(Nc2ccc(Cl)cc2)o1

InChI Key InChIKey=JOCQQTBGANYHKI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590139   

TargetLanosterol 14-alpha demethylase(Yeast)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50590139(CHEMBL5196919)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of candida albicans CYP51 using 7-ethoxyresorufin as fluorescent substrate incubated for 10 mins in the presence of NADPH by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50590139(CHEMBL5196919)
Affinity DataIC50: 3.05E+7nMAssay Description:Inhibition of human CYP3A4 using luciferin-IPA as substrate preincubated for 10 mins followed by NADPH addition and measured after 30 mins by lumines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed