BDBM50590055 CHEMBL5191638

SMILES [H][C@]12CN(CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2)C(=O)OC1COC1

InChI Key InChIKey=CJRYSMJZFNKLIF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50590055   

TargetSon of sevenless homolog 1(Human)
Wuhan University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50590055(CHEMBL5191638)
Affinity DataIC50: 78nMAssay Description:Inhibition of SOS1 in human DLD-1 cells assessed as reduction in ERK phosphorylation incubated for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed