BDBM50589996 CHEMBL5182683

SMILES CC(C)(CCCCCc1cc(cc(c1)/C=C/C=C\2/C[C@H](C[C@@H](C2=C)O)O)CCCCCC(C)(C)O)O

InChI Key InChIKey=KAXCFKOQLQAHBM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50589996   

Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50589996(CHEMBL5182683)
Affinity DataEC50:  3nMAssay Description:Induction of CYP24A1 (unknown orgin) transcriptional activity trasfected in human MCF7 cells incuabted for 48 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50589996(CHEMBL5182683)
Affinity DataIC50: 15.7nMAssay Description:Competitive binding affinity to His-tagged human VDR LBD (156 to 453 residues) expressed in Escherichia coli BL23 (DE3) cells in presence of 1,25D3 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed