BDBM50589980 CHEMBL5186687

SMILES OP(O)(=O)c1nc2ccc(cc2nc1P(O)(O)=O)C(=O)Nc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=ZFYHQFNAFQQBTC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50589980   

TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589980(CHEMBL5186687)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589980(CHEMBL5186687)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal his6-tagged MMP-1 expressed in HEK293 cells by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589980(CHEMBL5186687)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetStromelysin-1(Human)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589980(CHEMBL5186687)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed