BDBM50589764 CHEMBL5196873

SMILES O=C1CCc2ccccc2N1CCCN1CCN(CC1)c1ccccn1

InChI Key InChIKey=UWUBDOPGNONVDN-UHFFFAOYSA-N

Data  3 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50589764   

TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50589764(CHEMBL5196873)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as inhibition of dopamine-induced beta arrestin-2 recruitment p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50589764(CHEMBL5196873)
Affinity DataEC50:  8.5nMAssay Description:Partial agonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as G0 protein activation measured after 2.5 mins by BRET a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50589764(CHEMBL5196873)
Affinity DataEC50:  12nMAssay Description:Partial agonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as Gi protein activation measured after 2.5 mins by BRET a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50589764(CHEMBL5196873)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]N-methylspiperone from human D4.4 receptor expressed in HEK293T cell membrane incubated for 1 hr by MicroBeta scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50589764(CHEMBL5196873)
Affinity DataKi:  2.57E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D3R receptor expressed in HEK293T cell membrane incubated for 1 hr by MicroBeta scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50589764(CHEMBL5196873)
Affinity DataKi:  2.75E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293T cell membrane incubated for 1 hr by MicroBeta scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed