BDBM50589703 CHEMBL5196906

SMILES NCC(=C/F)[C@H]1Cc2ccccc2O1

InChI Key InChIKey=ONNKLUIZGFVIEE-UHFFFAOYSA-N

Data  2 KI  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50589703   

TargetAmine oxidase [flavin-containing] B(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant MAO-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProtein-lysine 6-oxidase(Bovine)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of bovine aorta LOXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human LOXL-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Mouse)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of mouse muscle MAO-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetMembrane primary amine oxidase(Rat)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataIC50: 5nMAssay Description:Inhibition of rat SSAOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetAmine oxidase [copper-containing] 2(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataIC50: 29nMAssay Description:Inhibition of SSAO in HMEC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetD-amino-acid oxidase(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant DAOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant MAO-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetAmine oxidase [copper-containing] 2(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human SSAOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataKi:  8nMAssay Description:Time dependent inhibition of human recombinant MAO-B assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetAmine oxidase [copper-containing] 2(Human)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50589703(CHEMBL5196906)
Affinity DataKi:  710nMAssay Description:Time dependent inhibition of human recombinant SSAO assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed