BDBM50589691 CHEMBL5202851

SMILES COC(C)(C)C(=O)NC(=O)Nc1ccc(Oc2ccnc(c2)-c2ccc(C)nc2)c(C)n1

InChI Key InChIKey=PCXFPRAKEYSDMS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50589691   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589691(CHEMBL5202851)
Affinity DataIC50: 21nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589691(CHEMBL5202851)
Affinity DataIC50: 674nMAssay Description:Inhibition of N-terminal GST-tagged PDGFRalpha (unknown origin) (550 to 1089 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589691(CHEMBL5202851)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of N-terminal GST-tagged PDGFRbeta (unknown origin) (557 to 1106 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589691(CHEMBL5202851)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed