BDBM50589582 CHEMBL5176195

SMILES Cc1c(CC[S+]([O-])CCO)cc(-c2ccc(cc2)S(C)(=O)=O)n1-c1ccc(F)c(F)c1

InChI Key InChIKey=QUSFFGBNDHUOAX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50589582   

TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589582(CHEMBL5176195)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589582(CHEMBL5176195)
Affinity DataIC50: 140nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed