BDBM50589568 CHEMBL5185401

SMILES COc1cc(S)c(cc1OC)\N=N\c1ccc(C#N)c(c1)C#N

InChI Key InChIKey=VDQVKUIRVGKTKH-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50589568   

TargetAmine oxidase [flavin-containing] A(Human)
University of Khartoum

Curated by ChEMBL
LigandPNGBDBM50589568(CHEMBL5185401)
Affinity DataIC50: 5.56E+4nMAssay Description:Inhibition of human MAO-A assessed as inhibition of H2O2 production using p-tyramine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Khartoum

Curated by ChEMBL
LigandPNGBDBM50589568(CHEMBL5185401)
Affinity DataIC50: 740nMAssay Description:Inhibition of human MAO-B assessed as inhibition of H2O2 production using p-tyramine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Khartoum

Curated by ChEMBL
LigandPNGBDBM50589568(CHEMBL5185401)
Affinity DataKi:  78nMAssay Description:Mixed competitive inhibition of human MAO-B using p-tyramine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed