BDBM50589476 CHEMBL5185809

SMILES O=C(Nc1ccc2[nH]cnc2c1)c1csc(Nc2ccccc2)n1

InChI Key InChIKey=WROAXSSJZFFCSV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50589476   

TargetDual specificity protein kinase CLK4(Human)
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50589476(CHEMBL5185809)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50589476(CHEMBL5185809)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of CLK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50589476(CHEMBL5185809)
Affinity DataIC50: 14nMAssay Description:Inhibition of CLK4 (unknown origin) assessed as reduction in SRSF10 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50589476(CHEMBL5185809)
Affinity DataIC50: 24nMAssay Description:Inhibition of CLK4 (unknown origin) assessed as reduction in SRSF1 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50589476(CHEMBL5185809)
Affinity DataIC50: 44nMAssay Description:Inhibition of CLK1 (unknown origin) assessed as reduction in SRSF10 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed