BDBM50589295 CHEMBL246237::Phthalazin-5-Amine::US12338238, Example 37

SMILES Nc1cccc2cnncc12

InChI Key InChIKey=IXASUUHIFCTEJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50589295   

TargetAspartate aminotransferase, cytoplasmic(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50589295(CHEMBL246237 | Phthalazin-5-Amine | US12338238, Ex...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetNAD(+) hydrolase SARM1(Human)
Disarm Therapeutics

US Patent
LigandPNGBDBM50589295(CHEMBL246237 | Phthalazin-5-Amine | US12338238, Ex...)
Affinity DataIC50: 2.25E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2025
Entry Details
Go to US Patent