BDBM50589184 CHEMBL5177673

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccc4ncccc4c3)cc2)n(n1)-c1ccc2ncccc2c1

InChI Key InChIKey=MCPVQJIWQOAKGR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50589184   

TargetTyrosine-protein kinase ABL1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50589184(CHEMBL5177673)
Affinity DataIC50: 345nMAssay Description:Inhibition of NanoLuc-tagged ABL1 wild type (unknown origin) expressed in HEK293 cells by NanoBRET TE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50589184(CHEMBL5177673)
Affinity DataIC50: 12nMAssay Description:Inhibition of AXL (unknown origin) using peptide substrate in presence of ATP by radiometric HotSpot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed